Increasing the competitiveness of the Russian economy is achieved through the creation of innovative territorial centers and clusters in the regions. In the Far East, territories of advanced social and economic development (TADs) are being created. At the same time, the role of the centers of innovative, technological and social development of the regions is assigned to higher educational institutions. Entrepreneurial activities aimed at commercializing research and development projects are added to the traditional functions of the university (education and research). The university becomes not only a breeding ground of specialists for the country’s national economy, but must also act as a forum for the development of innovation-oriented entrepreneurship. The objectives of the university should be to create an enabling environment and conditions for the implementation of scientific activities, to create an effective infrastructure for research, to involve the student community in fundamental and applied research, to commercialize innovations. Moreover, the end goal of intellectual scientific activity should be the result embodied not only in the form of new knowledge, prototypes, etc., but also novelties in the market aimed at consumers providing income. This new role of universities requires modernizing the educational process itself, as well as curricula and training programs for students. The purpose of the study is to analyze the competences formed by students in the process of educational activity and aimed at the development of innovative entrepreneurship in the region. We have considered the essence and stages of innovative entrepreneurship. The problems of training bachelors and masters in this field have been determined based on the study of curricula of training programs of the Komsomolsk-on-Amur State Technical University. The above analysis algorithm can be used by universities to justify the need for additional training of students for the development of innovative entrepreneurship. Recommendations have been developed for improving the training of students, consisting in the development of comprehensive programs of elective disciplines and project-oriented training of engineering students. The directions of further research are related to identifying the factors that inhibit the development of innovative entrepreneurial activity among students and determining the needs of students in obtaining specific knowledge and skills necessary for conducting innovative entrepreneurial activities.