The article discusses the tools for forming an effective energy infrastructure for regional development from the standpoint of ensuring sustainable socio-economic development of the territories. We have determined the role of infrastructural support in the regional development as a regulator, a factor and a condition for the development of the territories. It is emphasized that the infrastructural support of the territory is the most important tool of managerial influences on all aspects of territorial organization and regional development. The purpose of this article is to identify the directions for developing the tools of energy infrastructure support in the region for sustainable socio-economic development of territories. We have assessed the energy infrastructure of regional development based on indicators of accessibility of the energy infrastructure and the efficiency of the procedures for connection of electricity in Russia in 2011–2016, the depreciation of fixed assets in Russia, energy efficiency. Infrastructural energy support of regional development for the 2011–2016 period was studied using the Sverdlovsk region as an example, which made it possible to formulate the main directions for the development of effective infrastructure energy support of the regional development: the formation of a single electric grid area, the development of tools for managing the development of the regional electric power infrastructure, the improvement of the mechanisms for interaction of energy companies with the authorities. To solve the identified problems of the development of the electric power infrastructure (on the example of the Sverdlovsk region), we have proposed tools for forming an effective infrastructural support of the regional development, consisting of improving procedures for technological connection, changing the general approaches to technological connection, consolidating electric grid assets in the territory. A model for managing the development of the electric power infrastructure in the economic space of the region is proposed; the model’s theoretical and methodological basis were the provisions of the metasystem approach. It is emphasized that the directions of the development of effective infrastructure power support tools largely cover the institutional aspects, the development of the toolkit consists in introducing a systemic approach, as well as the principles of marketing and social partnership in the management of the infrastructure complex, the relationship of the subjects of management. The research basis is represented by the provisions of the scientific paradigm of socio-economic development, which is based on the principles of synergy, institutional and evolutionary analysis. The reproductive, institutional and systemic methodological approaches have been used in the study.