In this paper, we consider solutions of a fundamental nature, such as, for example, the choice of a business model. The consequences of implementing these decisions affect the long-time performance of the enterprise. The problem of interaction between enterprises is interdisciplinary. We have identified significant integration solutions and trends emerging as a result of development of digital technologies. We have also analyzed the influence of separate factors for different levels of enterprise functioning in the digital environment. We have formulated the opportunities for building an enterprise integration strategy in the current conditions. The strategy of network coordination of economic ties between enterprises in the digital environment is implemented by creating or joining multilateral platforms. It is characterized by horizontal connections. The principle of operation of multilateral platforms is that one enterprise, the platform owner, provides access to their contractors with offers of products or services to interested partners. These proposals complement the company's proposals. The modern digital economy allows building more effective interaction of enterprises of different level based on multilateral business models. A necessary condition for effective coordination of production of products and services of different enterprises is development and mandatory application of a unified system of standards and protocols for the exchange of data between economic agents. Implementing strategic decisions based on multilateral platforms allows taking advantage of digital analysis, information processing and making administrative decisions with large data sets. This also reduces the costs of selecting suppliers and marketing research and reduces the risk of adverse events.