On the basis of a wide range of indicators in dynamics for 2006-2010, investigated rating and level of socio-economic asymmetry of the federal districts of the Russian Federation and the subjects of the Siberian Federal District. Level of socio-economic asymmetry in the coming post-crisis period has decreased, but it is possible a sharp increase in its value in the medium term. Prospects for post-crisis development of the objects can not be too optimistic due to the lack of structural reforms in the economy and a significant drop in investment.